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I started
this website for several reasons ... (1) to make certain running information readily
available to section III fans and (2) to provide
a ranking and analysis of running performances that is not available
anywhere else.
I'm a 1968 graduate of Tully High. During the
1970's, I sent a fair amount of time training for the decathlon ...
overall, I was barely mediocre with top scores around
6000. However, I was able to meet many great track people and learn
from them. I learned a great deal about weight lifting (and how it
helps in track) from Liverpool Coach Oscar Jensen (Oscar is now
the Baldwinsville boys track coach). In contrast to most high school coaches, I'm not
a school teacher ... I'm an environmental scientist with degrees
from Clarkson University ... I've outlined my professional career
below. I was a volunteer coach at Tully High for many years helping
with cross country and track & field ... I got to see Lopez Lomong up
close and personal for his entire high school career at Tully.
I work for SRC, Inc. (formerly Syracuse Research Corporation) as an environmental scientist. Our
main corporate website is available at
http://www.srcinc.com/ ... (2018 update ... I'm currently a
"casual employee" at SRC which means I am mostly retired ... I still get
called back to work for various projects I worked on in the past).
Primary funding for the corporate division
(Environmental Health Analysis) comes from U.S. Environmental Protection
Agency (EPA) and other regulatory agencies. My major
responsibility is development of methodology and computer software to
predict physical and chemical properties of organic compounds for
assessment of environmental fate and transport. The software I've
developed is used by the U.S. EPA (evaluation of Toxic Substances Control
Act and pre-manufacture
chemicals), German EPA, Danish EPA, and other governmental regulatory
agencies around the world (more than 30 countries). Pharmaceutical firms use the software for high-throughput
screening and combinatorial chemistry during the drug design evaluation. I
maintain large chemical property databases that I use for data analysis
and pattern recognition ... SRC sold the primary software to the USEPA in
2000, but we still maintain and update it for EPA ... It can be
downloaded for free from the EPA web-site at:
https://www.epa.gov/tsca-screening-tools/download-epi-suitetm-estimation-program-interface-v411
I'm the primary author of nearly a dozen
scientific journal articles describing chemical structure estimation
methodologies. Articles have been published in peer-reviewed journals such
as the Journal of Pharmaceutical Sciences, Environmental Science &
Technology, Environmental Toxicology & Chemistry, and Chemosphere.
I'm the co-author of two books ["Handbook of Environmental
Degradation Rates" (Lewis Publishers) and "Handbook of Physical
Properties of Organic Compounds (CRC Press)] and contributing author to
about half a dozen other books. I also peer-review several manuscript
submissions for various journals each year. I have written the
Environmental section for about 500 chemicals in the National Library of
Medicine's Hazardous Substances Databank (HSDB).
Publications and Presentations
(as of 2015)
Tunkel J; Lee WH; Cassidy L; Lynch D; Fehrenbacher C; Savage S; Meylan
W; Drogo J; Mayo-Bean, K. (2015) The redesign of EPISuite™ as a
web-based tool. Presented at the Society of Environmental Toxicology and
Chemistry (SETAC) annual meeting, November 1-5, 2015, Salt Lake City,
UT.
Boethling RS; Meylan WM. (2013) How accurate are physical property
estimation programs for organosilicon compounds? Environ Toxicol Chem
32(11):2433-2440.
Boethling R; Davies C; Fehrenbacher C; Lavoie E; Libelo L; Sommer E;
Henry T; Howard P; Meylan W; Morlacci L; Tunkel J; Webb T; Mayo K; Waugh
W; Zeeman M. (2010) Comment on “More of EPA’s SPARC online
calculator—the need for high-quality predictions of chemical
properties”. Environ Sci Technol 44:7745.
Arnot JA; Meylan W; Tunkel J; Howard PH; Mackay D; Bonnell M; Boethling
RS. (2009) A quantitative structure-activity relationship for predicting
metabolic biotransformation rates for organic chemicals in fish. Environ
Toxicol Chem 28(6):1168-1177.
Meylan W; Boethling R; Aronson D; Howard P; Tunkel J. (2007) Chemical
structure-based predictive model for anaerobic biodegradation potential.
Environ Toxicol Chem 26(9):1785-1792.
Tunkel J; Meylan W; Adkins K; Mayo-Bean K. (2006) Chemical
categorization using the Analog Identification Methodology (AIM).
Presented at the 12th international workshop on quantitative
structure-activity relationships in environmental toxicology, May 8-12,
2006, Lyon, France.
Howard P; Meylan W; Aronson D; Stiteler W; Tunkel J; Comber M; Parkerton
TF. (2005) A new biodegradation prediction model specific to petroleum
hydrocarbons. Environ Toxicol Chem 24(8):1847-1860.
Meylan WM; Howard PH. (2005) Estimating octanol-air partition
coefficients with octanol-water partition coefficients and Henry's law
constants. Chemosphere 61:640-644.
Boethling RS; Howard PH; Meylan WM. (2004) Finding and estimating
chemical property data for environmental assessment. Environ Toxicol
Chem 23:2290-2308.
Tunkel J; Mayo K; Meylan W. (2003) EPI methodology and the PBT Profiler.
Presented at the persistence, bioconcentration, and toxicity ETAD/CPMA
workshop on PBT modeling, May 15-16, 2003, Newport, RI.
Meylan WM; Howard PH. (2003) A review of quantitative structure-activity
relationship methods for the prediction of atmospheric oxidation of
organic chemicals. Environ Toxicol Chem 22(8):1724-1732.
Rosenberg SA; Hueber HE; Aronson D; Gouchie S; Howard PH; Meylan WM;
Tunkel JL. (2003) Syracuse Research Corporation's chemical information
databases: Extraction and compilation of data related to environmental
fate and exposure. Sci Technol Libr 23(4):73-87.
Howard P; Meylan W. (2001) Toxic chemicals: assessing environmental fate
and exposure. Chem Eng (N Y) 108(3):91-96.
Meylan WM; Howard PH. (2000) Estimating log P with atom/fragments and
water solubility with log P. 19:67-84.
Griffin S; Goodrum PE; Diamond GL; Meylan W; Brattin WJ; Hassett JM.
(1999) Application of a probabilistic risk assessment methodology to a
lead smelter site. Hum Ecol Risk Assess 5(4):845-868.
Meylan WM; Howard PH; Boethling RS; Aronson D; Printup H; Gouchie S.
(1999) Improved method for estimating bioconcentration/bioaccumulation
factor from octanol/water partition coefficient. Environ Toxicol Chem
18(4):664-672.
Howard PH; Walker JD; Boethling RS; Meylan WM. (1999) Role of QSARs in
the identification of persistent, bioaccumulative and toxic (PBT)
substances. In: Walker JD, ed. QSAR 98. Proceedings of the 8th
International Workshop on Quantitative Structure-Activity Relationships
in the Environmental Sciences, 16-20 May 1998, Baltimore, MD. Pensacola,
FL: SETAC Press.
Meylan WM; Howard PH; Boethling RS; Aronson D; Printup H; Gouchie S.
(1999) Estimating bioconcentration factor from log Kow and molecular
structure. In: Walker JD, ed. QSAR 98. Proceedings of the 8th
International Workshop on Quantitative Structure-Activity Relationships
in the Environmental Sciences, 16-20 May 1998, Baltimore, MD. Pensacola,
FL: SETAC Press.
Howard PH; Meylan WM, eds. (1997) Handbook of physical properties of
organic chemicals. Boca Raton, FL: Lewis Publishers.
Howard PH; Meylan WM. (1997) Prediction of physical properties,
transport, and degradation for environmental fate and exposure
assessment. In: Chen F, Schuurmann G, eds. Quantitative
structure-activity relationships in environmental sciences. Pensacola,
FL: SETAC Press. 185-205.
Meylan WM; Howard PH; Boethling RS. (1996) Improved method for
estimating water solubility from octanol/water partition coefficient.
Environ Toxicol Chem 15(2):100-106.
Durkin PR; Rubin L; Withey J; Meylan W. (1995) Methods of assessing
dermal absorption with emphasis on uptake from contaminated vegetation.
Toxicol Ind Health 11(1):63-79.
Meylan WM; Howard PH. (1995) Atom/fragment contribution method for
estimating octanol-water partition coefficients. J Pharm Sci
84(1):83-92.
Boethling RS; Howard PH; Meylan W; Stiteler W; Beauman J; Tirado N.
(1994) Group contribution method for predicting probability and rate of
aerobic biodegradation. Environ Sci Technol 28:459-465.
Howard PH; Michalenko EM; Basu DK; Sage GW; Meylan WM; Beauman JA;
Jarvis WF; Gray DA. (1993) Handbook of environmental fate and exposure
data for organic chemicals. 4. Solvents 2. Chelsea, MI: Lewis
Publishers.
Meylan WM; Howard PH. (1993) Computer estimation of the atmospheric
gas-phase reaction rate of organic compounds with hydroxyl radicals and
ozone. Chemosphere 26(12):2293-2299.
Howard PH; Boethling RS; Stiteler WM; Meylan WM; Hueber AE; Beauman JA;
Larosche ME. (1992) Predictive model for aerobic biodegradability
developed from a file of evaluated biodegradation data. Environ Toxicol
Chem 11:593-603.
Meylan W; Howard PH; Boethling RS. (1992) Molecular topology/fragment
contribution method for predicting soil sorption coefficients. Environ
Sci Technol 26(8):1560-1567.
Rubin L; Durkin P; Meylan W; Withey JR. (1992) An analysis and
validation of methods for assessing dermal uptake of pesticides from
contaminated surfaces. Toxicologist 13(1):281.
Howard PH; Michalenko EM; Jarvis WF; Basu DK; Sage GW; Meylan WM;
Beauman JA; Gray DA. (1991) Handbook of environmental fate and exposure
data for organic chemicals. Chelsea, MI: Lewis Publishers.
Howard PH; Boethling RS; Jarvis WF; Meylan WM; Michalenko EM. (1991)
Handbook of environmental degradation rates. Chelsea, MI: Lewis
Publishers, Inc.
Howard PH; Boethling RS; Stiteler W; Meylan W; Beauman J. (1991)
Development of a predictive model for biodegradability based on BIODEG,
the evaluated biodegradation data base. Sci Total Environ
109/110:635-641.
Meylan WM; Howard PH. (1991) Bond contribution method for estimating
Henry's Law constant. Environ Toxicol Chem 10:1283-1293.
Howard PH; Jarvis WF; Sage GW; Basu DK; Gray DA; Meylan W; Crosbie EK.
(1989) In: Howard, PH, ed. Handbook of environmental fate and exposure
data for organic chemicals. 1. Large production and priority pollutants.
Chelsea, MI: Lewis Publishers.
Howard PH; Hueber AE; Mulesky BC; Crisman JS; Meylan W; Crosbie E; Gray
DA; Sage GW; Howard KP; LaMacchia A; Boethling R; Troast R. (1986)
BIOLOG, BIODEG, and FATE/EXPOS: New files on microbial degradation and
toxicity as well as environmental fate/exposure of chemicals. Environ
Toxicol Chem 5:977-988.
Meylan W; Papa L; DeRosa CT; Stara JF. (1986) Chemical of current
interest propylene oxide: Health and environmental effects profile.
Toxicol Ind Health 2:219-257.
Santodonato J; Bosch S; Meylan W; Becker J; Neal M. (1985) Monograph on
human exposure to chemicals in the workplace: 1,4-dioxane. PB86131414.
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